Synthesis and degradation rate constant of 3OHC14-HSL (3OHC14-homo-serine lactone)

Range synthesis rate 3,000nM/hr: degradation rate 0.017/hour
Organism Bacteria Rhizobium leguminosarum
Reference Pai A, You L: Optimal tuning of bacterial sensing potential. Molecular systems biology 2009, 5(286) :286 doi: 10.1038/msb.2009.43. Supplementary Text 2 p.30 middle of pagePubMed ID19584835
Primary Source Lithgow JK et al., (2000) The regulatory locus cinRI in Rhizobium leguminosarum controls a network of quorum-sensing loci. Molecular microbiology 37: 81-97.PubMed ID10931307
Comments Supplementary Text 2 p.30 middle of page:"Synthesis rate: Based on cinI’s homology to luxI (primary source) , [investigators] assume k = 3×10^3 nM hr-1. Degradation rate constant: [Investigators] assume da=1.7×10^-2 hr^-1 (see note on degradation of C16:1-HSL above)."
Entered by Uri M
ID 112010