Comments |
p.871 left column top paragraph:"As
in other fields of molecular biology, Escherichia coli became the standard model for ribosome studies, with useful supplementary information derived from other bacteria and yeast. An overview of the components in ribosomes from the different domains of life is given in TABLE 1." Caption to table:"Ribosomes from all domains of life function in essentially the same manner. Bacterial and
archaeal ribosomes are approximately the same size, whereas the ribosomes in Eukarya are
much larger. Differences in rRNA and r-protein components allow antibiotics and cytotoxins to
exhibit specificity for the ribosomes of one domain. Chloroplast ribosomes (not shown) are
structurally closest to the bacterial domain. Mitochondrial ribosomes (based on the rat genome
sequence) have evolved away from the other structures, including their cytoplasmic
counterparts, and contain a larger complement of r-proteins relative to the rRNA." |