| Comments |
p.767 left column bottom paragraph:"At different synapses, electrophysiology suggests that 10–70 AMPA receptors are opened by a single vesicle (BNID 111653), while immunogold labels 8–40 postsynaptic AMPA receptors (Nusser et al., 1998). These numbers are underestimates, because the open probability of the receptors at the peak of the synaptic current is less than 1 (even in saturating glutamate) and because some receptors will not be labeled by immunocytochemistry. The probable true density is thus ~20–100 receptors per bouton." AMPA receptor=a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor |