Number of ribosomes in E. coli K12 cell that grows with a doubling time of about 30 minutes

Range ~50,000 ribosomes/cell
Organism Bacteria Escherichia coli
Reference Mackie GA RNase E: at the interface of bacterial RNA processing and decay. Nat Rev Microbiol. 2013 Jan11(1):45-57. doi: 10.1038/nrmicro2930. p.51 box 2PubMed ID23241849
Primary Source Bakshi S, Siryaporn A, Goulian M, Weisshaar JC. Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells. Mol Microbiol. 2012 Jul85(1):21-38. doi: 10.1111/j.1365-2958.2012.08081.x.PubMed ID22624875
Comments "In quantitative terms, where does RNase E invest its enzymatic turnovers? This can be estimated with the following assumptions. In a culture of Escherichia coli K12 that grows with a doubling time of about 30 minutes, there will be approximately 50,000 ribosomes [primary source], 375,000 tRNAs [BNID 108611] (7.5 per ribosome) and perhaps a single to at most ten copies of each of the ~2,000 mRNAs per cell."
Entered by Uri M
ID 111527