| Value |
0.9
% larger
Range: ±0.1 % larger
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Stewart EJ, Madden R, Paul G, Taddei F. Aging and death in an organism that reproduces by morphologically symmetric division. PLoS Biol. 2005 Feb3(2):e45. p.0298 right column top paragraphPubMed ID15685293
|
| Method |
"To determine if E. coli experiences aging related to the inheritance of the old pole, [investigators] followed individual exponentially growing cells in an automated fluorescence microscopy system through up to nine generations of growth and reproduction, measuring the physical parameters of each cell over time." |
| Comments |
"Two factors from this same dataset demonstrate the lack of a juvenile phase in E. coli. First, comparison of the progeny cells shows that the new pole cell is slightly larger on average (0.9±0.1%: P<0.00001, t = 5.62, df = 7952) than the old pole cell (the contrary would be expected in the presence of a juvenile phase). Second, the young pole cell is marginally more likely to divide sooner than the old pole cell (in about 15% of the cases cells divide within the same 2-min time point: of those where the two cells divide in different time points, 54% of the time the new pole cell divides first [significant: p<0.00001, t = 5.02, df= 4812]), which is also not consistent with a phase where the young cell must grow or differentiate before reproduction." |
| Entered by |
Uri M |
| ID |
111489 |