Degree to which overall transcription rate is slower in stationary phase compared to logarithmic phase

Range 3 - 5 times slower
Organism Budding yeast Saccharomyces cerevisiae
Reference Lemons JM et al., Quiescent fibroblasts exhibit high metabolic activity. PLoS Biol. 2010 Oct 19 8(10):e1000514. doi: 10.1371/journal.pbio.1000514. p.1 right column top paragraphPubMed ID21049082
Primary Source Choder M (1991) A general topoisomerase I-dependent transcriptional repression in the stationary phase in yeast. Genes Dev 5: 2315–2326.PubMed ID1660829
Comments "In addition, the overall transcription rate is three to five times slower in stationary-phase than in logarithmic-phase cultures [primary source], and protein synthesis is reduced to approximately 0.3% of the rate in logarithmically growing cultures [BNID 111471]. Therefore, the quiescent cells within a stationary-phase culture of yeast likely represent an example of a quiescent cell that has significantly reduced its metabolic activity."
Entered by Uri M
ID 111470