Turnover number of ion transport sites on red blood cell membrane at 38°C

Value 50000 ions/site/sec
Organism Human Homo sapiens
Reference Brahm J. Temperature-dependent changes of chloride transport kinetics in human red cells. J Gen Physiol. 1977 Sep70(3):283-306. p.303 2nd paragraphPubMed ID19556
Comments P.303 2nd paragraph: "It may be of interest to compare the turnover rate for chloride transport in red cell membranes with the turnover rates of ion transport through modified bimolecular lipid membranes. If one assumes that each red cell membrane carries 10^6 transport sites, the turnover number per site is 5×10^4 ions/s at 38°C." Also, the 50,000/s was most likely an underestimate because the exchanger was running at sub-saturating substrate concentrations (Olaf Andersen, private communication).
Entered by Uri M
ID 111368