Number of genes on 11 plasmids studied

Value 430 genes
Organism Bacteria Borrelia burgdorferi
Reference Fraser et al., Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature. 1997 Dec 11 390(6660):580-6. abstract & p.581 right column 2nd paragraphPubMed ID9403685
Method "Here [researchers] summarize the results from sequencing, assembly and analysis of the linear chromosome and 11 plasmids."
Comments "Of 430 genes on 11 plasmids, most have no known biological function: 39% of plasmid genes are paralogues that form 47 gene families...The 11 plasmids [researchers] have described contain a total of 430 putative ORFs with an average size of 507 bp: plasmid G+C content ranges from 23.1% to 32.3%. Only 71% of plasmid DNA represents predicted coding sequences, a value significantly lower than that on the chromosome......Of the 430 plasmid ORFs, only 70 (16%) could be identified and these include membrane proteins such as OspA-D, decorin-binding proteins, the VlsE lipoprotein recombination cassette, and the purine ribonucleotide biosynthetic enzymes GuaA and GuaB."
Entered by Uri M
ID 111258