Average actin filament length in neuron

Value 0.55 μm Range: 204 subunits (~370 subunits per micrometer) μm
Organism Squid Loligo pealeii
Reference Bernstein BW, Bamburg JR. Actin-ATP hydrolysis is a major energy drain for neurons. J Neurosci. 2003 Jan 1 23(1):1-6. p.4 right column bottom paragraphPubMed ID12514193
Primary Source Fath KR, Lasek RJ (1988) Two classes of actin microfilaments are associated with the inner cytoskeleton of axons. J Cell Biol 107: 613–621.PubMed ID3417765
Comments "Assuming that total cellular actin concentration is 100µM, a filament end concentration of 2µM means there is an average of only 50 subunits per filament. This is significantly shorter than the estimate for the average filament length in neurons, which is 0.55µm or 204 subunits (~370 subunits per micrometer) (primary source)." See BNID 109294
Entered by Uri M
ID 110645