| Range |
~12,000–18,000 follicles /large intestine
|
| Organism |
Human Homo sapiens |
| Reference |
McConnell EL, Basit AW, Murdan S. Measurements of rat and mouse gastrointestinal pH, fluid and lymphoid tissue, and implications for in-vivo experiments. J Pharm Pharmacol. 2008 Jan60(1):63-70. p.64 left column bottom paragraphPubMed ID18088506
|
| Primary Source |
Langman, J. M, Rowland, R. (1986) The number and distribution of lymphoid follicles in the human large intestine. J. Anat. 149: 189–194 & Langman, J. M., Rowland, R. (1992) Density of lymphoid follicles in the rectum and at the anorectal junction. J. Clin. Gastroenterol. 14: 81–84 & Gebbers, J. O., Kennel, I., Laissue, J. A. (1992) Lymphoid follicles of the human large bowel mucosa: structures and function. Verh. Dtsch. Ges. Pathol. 76: 126–130PubMed ID3693106, 1556415, 1283242
|
| Comments |
"Like the small intestine, the colon contains
gut-associated lymphoid tissue. In man, there are approximately
339 Peyer’s patches (Cornes 1965 BNID 110511) in the small
intestine, and approximately 12,000–18,000 follicles in the
large intestine (primary sources). Presence of such a large number of follicles in
man’s colon implies the feasibility of vaccine uptake and
processing in the colon." |
| Entered by |
Uri M |
| ID |
110512 |