Percent of genome that are G-protein-coupled receptors (GPCRs)
| Range | ~4 % |
|---|---|
| Organism | Human Homo sapiens |
| Reference | Matthews JM, Sunde M. Dimers, oligomers, everywhere. Adv Exp Med Biol. 2012 747: 1-18. doi: 10.1007/978-1-4614-3229-6_1 p. 13 top paragraphPubMed ID22949108 |
| Comments | "Chemokines induce chemotaxis (cell movement) by binding to G-protein-coupled receptors (GPCRs), which are the most common cell surface receptors making up ~4% of the human genome (~800 human GPCRs). These receptors are integral membrane proteins with a common core of seven transmembrane a-helices, but the extra- and intracellular domains are widely varied." (Assuming there are 20,000 human genes) |
| Entered by | Uri M |
| ID | 109184 |