Percent of genome that are G-protein-coupled receptors (GPCRs)

Range ~4 %
Organism Human Homo sapiens
Reference Matthews JM, Sunde M. Dimers, oligomers, everywhere. Adv Exp Med Biol. 2012 747: 1-18. doi: 10.1007/978-1-4614-3229-6_1 p. 13 top paragraphPubMed ID22949108
Comments "Chemokines induce chemotaxis (cell movement) by binding to G-protein-coupled receptors (GPCRs), which are the most common cell surface receptors making up ~4% of the human genome (~800 human GPCRs). These receptors are integral membrane proteins with a common core of seven transmembrane a-helices, but the extra- and intracellular domains are widely varied." (Assuming there are 20,000 human genes)
Entered by Uri M
ID 109184