| Value |
0.4
fmol per cell
|
| Organism |
Mammalian tissue culture cell |
| Reference |
Outten CE, O'Halloran TV. Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis. Science. 2001 Jun 29 292(5526):2488-92. p.2491 middle column top paragraphPubMed ID11397910
|
| Primary Source |
Palmiter RD, Findley SD. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J. 1995 Feb 15 14(4):639-49. AND Suhy DA, Simon KD, Linzer DI, O'Halloran TV. Metallothionein is part of a zinc-scavenging mechanism for cell survival under conditions of extreme zinc deprivation. J Biol Chem. 1999 Apr 2 274(14):9183-92.PubMed ID7882967, 10092590
|
| Comments |
"Mammalian cells
in culture maintain a total zinc quota within a
narrow range around 0.4 fmol per cell, corresponding to a total cellular Zn(II) concentration in the millimolar range (primary sources)." |
| Entered by |
Uri M |
| ID |
108832 |