Number of DNA pol IV
| Range | ~200 Molecules/cell |
|---|---|
| Organism | Bacteria Escherichia coli |
| Reference | Hastings PJ et al., Competition of Escherichia coli DNA polymerases I, II and III with DNA Pol IV in stressed cells. PLoS One. 2010 May 27 5(5):e10862. doi: 10.1371/journal.pone.0010862. abstractPubMed ID20523737 |
| Comments | "Although normally present at approximately 200 molecules per cell, Pol IV is recruited to acts of DNA double-strand-break repair, and causes mutagenesis, only when at least two cellular stress responses are activated: the SOS DNA-damage response, which upregulates DinB approximately 10-fold, and the RpoS-controlled general-stress response, which upregulates Pol IV about 2-fold." |
| Entered by | Uri M |
| ID | 108718 |