Number of ATP involved if complete fusion of the vesicle and plasma membranes occurs
| Range | ~400 ATP/vesicle released |
|---|---|
| Organism | Eukaryotes |
| Reference | Attwell D, Laughlin SB. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab. 2001 Oct21(10):1133-45. p.1136 left column 3rd paragraphPubMed ID11598490 |
| Comments | "If complete fusion of the vesicle and plasma membranes occurs, this will be needed for exocytosis and endocytosis, resulting in 21 ATP being consumed. Control of endocytosis by clathrin, adaptor proteins, dynamin, and hsc70 also uses ATP. Approximately 400 molecules/vesicle are involved (Marsh and McMahon, 1999 PMID 10398591), so if each were phosphorylated once, 400 ATPs/vesicle released are needed." |
| Entered by | Uri M |
| ID | 108627 |