| Range |
~15 Unitless
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Bakshi S, Siryaporn A, Goulian M, Weisshaar JC. Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells. Mol Microbiol. 2012 Jul85(1):21-38. doi: 10.1111/j.1365-2958.2012.08081.x. p.22 right column 3rd paragraphPubMed ID22624875
|
| Primary Source |
Bernstein JA, Khodursky AB, Lin PH, Lin-Chao S, Cohen SN. Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A. 2002 Jul 23 99(15):9697-702PubMed ID12119387
|
| Comments |
"Taken together, [researchers] results strongly suggest that at
least in E. coli, most translation is not coupled with transcription
(the ‘co-transcriptional translation’ mechanism),
counter to a view common in the literature. Instead, the
data suggest that completed messages diffuse to find the
ribosome-rich regions where the bulk of translation
occurs. This is consistent with the fact that lifetime estimates
of mRNA in live bacteria exceed typical times
required for transcription of a message by a factor of 15 or
so (primary source)." |
| Entered by |
Uri M |
| ID |
108599 |