Number of copies of elongation factor EF-Tu

Range 13,000 molecules per cell
Organism Bacteria Staphylococcus aureus
Reference Maass S et al., Efficient, global-scale quantification of absolute protein amounts by integration of targeted mass spectrometry and two-dimensional gel-based proteomics. Anal Chem. 2011 Apr 1 83(7):2677-84. p.2681 left column top paragraphPubMed ID21395229
Method "[Researchers] combined targeted mass spectrometry for the accurate determination of absolute protein abundance of specific proteins with the resolving power of 2-D PAGE to obtain a global view of a large number of protein concentrations."
Comments "The elongation factor EF-Tu is present with 13,000 molecules per cell and is therefore one of the five most abundant proteins in S. aureus."
Entered by Uri M
ID 108412