Speed of molecular motor kinesin II

Value 0.4 μm/sec
Organism Sea urchin
Reference Scholey JM, Ou G, Snow J, Gunnarson A. Intraflagellar transport motors in Caenorhabditis elegans neurons. Biochem Soc Trans. 2004 Nov32(Pt 5):682-4. p.682 left column 2nd paragraphPubMed ID15493987
Primary Source Cole DG, Chinn SW, Wedaman KP, Hall K, Vuong T, Scholey JM. Novel heterotrimeric kinesin-related protein purified from sea urchin eggs. Nature. 1993 Nov 18 366(6452):268-70. & Wedaman KP, Meyer DW, Rashid DJ, Cole DG, Scholey JM. Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex. J Cell Biol. 1996 Feb132(3):371-80.PubMed ID8232586, 8636215
Comments This protein (kinesin 2) contains two heterodimerized N-terminal motor subunits, which move towards the plus ends of microtubules at 0.4 µm/s and have a non-motor subunit, the KAP, linked to their cargo-binding C-terminal ends [primary sources].
Entered by Uri M
ID 108069