Ribosome footprint

Range ~30 nucleotides
Organism Unspecified
Reference Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science. 2009 Apr 10 324(5924):218-23. p.218 middle column 2nd paragraphPubMed ID19213877
Primary Source Steitz JA. Polypeptide chain initiation: nucleotide sequences of the three ribosomal binding sites in bacteriophage R17 RNA. Nature. 1969 Dec 6 224(5223):957-64.PubMed ID5360547
Comments The position of a translating ribosome can be precisely determined by using the fact that a ribosome protects a discrete footprint [~30 nucleotides (nt)] on its mRNA template from nuclease digestion (primary source).
Entered by Uri M
ID 107925