Mutation rate

Range 2.1e-8 mutations/site/generation
Organism Nematode Caenorhabditis elegans
Reference Baer CF, Miyamoto MM, Denver DR. Mutation rate variation in multicellular eukaryotes: causes and consequences. Nat Rev Genet. 2007 Aug8(8):619-31. p.623 left column bottom paragraphPubMed ID17637734
Primary Source [49] Denver DR, Morris K, Lynch M, Thomas WK. High mutation rate and predominance of insertions in the Caenorhabditis elegans nuclear genome. Nature. 2004 Aug 5 430(7000):679-82.PubMed ID15295601
Method Mutation accumulation (MA) lines
Comments p.623 left column bottom paragraph: "A survey of mutations in a long-term set of C. elegans MA lines revealed a mutation rate (2.1×10^–8 per site per generation) that is approximately one order of magnitude greater than the average of previous reporter gene estimates for this species [primary source]."
Entered by Uri M
ID 107888