| Range |
4 to 5 amino acids/sec/translating ribosome
|
| Organism |
Metazoa animals |
| Reference |
Piques et al., Ribosome and transcript copy numbers, polysome occupancy and enzyme dynamics in Arabidopsis. Mol Syst Biol. 2009 5: p.11 right column 3rd paragraphPubMed ID19888209
|
| Primary Source |
Lodish HF, Jacobsen M. Regulation of hemoglobin synthesis. Equal rates of translation and termination of - and -globin chains. J Biol Chem. 1972 Jun 10 247(11):3622-9. AND Palmiter RD. Differential rates of initiation of conalbumin and ovalbumin messenger ribonucleic acid in reticulocyte lysates. J Biol Chem. 1974 Nov 10 249(21):6779-87.PubMed ID4624122, 4420185
|
| Comments |
Literature values for the rate of ribosome progression in
eukaryotic cells vary from 1–8 amino acids per second per
translating ribosome, depending on the cellular conditions and
the mRNA (for reviews, see Ryazanov et al, 1991 Mathews
et al, 2007), with typical values of 4–5 for animal cells at
25–26°C (e.g. primary sources) and
7–8 for yeast cells at 30°C (e.g. Arava et al, 2003). |
| Entered by |
Uri M |
| ID |
107784 |