Number of copies of the ribosomal RNA locus in the diploid human genome

Range ~300 Copies
Organism Human Homo sapiens
Reference Editor: Dr. Robert A. Meyers, Encyclopedia of Molecular Cell Biology and Molecular Medicine, Dean A. Jackson, The Cell Nucleus: Biogenesis, Structure, and Function, p.28 right column bottom paragraph
Comments Each diploid human genome has about 300 copies of the ribosomal RNA locus. Each locus contains a single transcription unit of 13.3 kb, which is processed post-transcriptionally to generate three RNA molecules – the 28S, 18S, and 5.8S (in vertebrates) rRNAs – which, together with 5S RNA, are the structural RNAs that dictate ribosome assembly and function.
Entered by Uri M
ID 107500