| Range |
~8 Minutes
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Dill KA, Ghosh K, Schmit JD. Physical limits of cells and proteomes. Proc Natl Acad Sci U S A. 2011 Nov 1 108(44):17876-82 p.17880 right column bottom paragraphPubMed ID22006304
|
| Method |
If every protein molecule in
E. coli were a ribosomal protein, then each ribosome (a 55-protein
complex of about 7,400 amino acids) would need only to
synthesize its own 55 proteins in series, not 3 million. In this limit,
E. coli could replicate in around 8 min [7,400/15aa/sec]. |
| Comments |
This is a
simple “ballpark” estimate, not expected to be good to better
than a factor of two or three. In reality, E. coli is able to replicate at a speed that is exceedingly close to this maximum possible physical
speed limit. |
| Entered by |
Uri M |
| ID |
107063 |