| Method |
"[Researchers] examined proteomes from 5 eukaryotic species, 16 archaeal species and 67 bacterial species [table 1 link ]. For human sequences, [they] used the Ensembl genome database (12) Release 29.35b collection of ‘known and new’ proteins based on the NCBI 35 assembly of the human genome. These proteomes contained 104,394 eukaryotic proteins, 37,141 archaeal proteins and 191,518 bacterial proteins. Protein lengths were compared with respect to taxonomic, functional and ecological classes...[They] evaluated results using the set of proteins classified in the COG (Clusters of Orthologous Groups of proteins) database and the set of genomic proteins included in the Pfam database of functional/structural domain alignments verified by human intervention (Pfam-A)." |