Rule of thumb for diffusion rate of DNA in water according to nu. of bp

Range Dw=4.9×10^-6 cm^2/sec×[bp size]^-0.72
Organism Generic
Reference Lukacs GL, Haggie P, Seksek O, Lechardeur D, Freedman N, Verkman AS. Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem. 2000 Jan 21 275(3):1625-9. p.1626 right column 3rd paragraph and p.1627 fig. 2bPubMed ID10636854
Method Empirically derived from FRAP - (fluorescence recovery after photobleaching) experiments
Comments Note-"[bp size]^-0.72" is in the numerator. See BNID 106089
Entered by Uri M
ID 106087