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Number of genes that encode proteins that are able to bind drug-like molecules

Value	3000 Unitless
Organism	Human Homo sapiens
Reference	Fleming A, Noda T, Yoshimori T, Rubinsztein DC. Chemical modulators of autophagy as biological probes and potential therapeutics. Nat Chem Biol. 2011 Jan7(1):9-17. p.16 left column bottom paragraphPubMed ID21164513
Primary Source	Hopkins AL, Groom CR. The druggable genome. Nat Rev Drug Discov. 2002 Sep1(9):727-30.PubMed ID12209152
Comments	Although the modern pharmacopoeia comprises in excess of 21,000 FDA–approved drug products, when duplications (for example, different salts of the same active compound) are disregarded, it is calculated that there are only 1,204 small-molecule and 166 biological drugs currently available (Overington et al., 2006 PMID 17139284).
Entered by	Uri M
ID	106071