No. of genes

Value 4233 genes Range: Table - link genes
Organism Bacteria Bacillus subtilis
Reference Rogozin IB et al., Congruent evolution of different classes of non-coding DNA in prokaryotic genomes. Nucleic Acids Res. 2002 Oct 1 30(19):4264-71. p.4266 table 1PubMed ID12364605
Primary Source Tatusov RL et al., The COG database: new developments in phylogenetic classification of proteins from complete genomes. Nucleic Acids Res. 2001 Jan 1 29(1):22-8. COG - Clusters of Orthologous Groups of proteins (NCBI) link PubMed ID11125040
Method "[Researchers] analyzed the intergenic distances in 50 completely sequenced bacterial and archaeal genomes using the COG database [primary source] to limit the study to pairs of robustly predicted genes."
Comments "The number of genes and genome length vary widely among prokaryotes the smallest of the analyzed genomes, M. genitalium, had 517 predicted genes, whereas the largest one, M. loti, had 7596 predicted genes. The average gene density per 1000 nucleotides is close to 1.0 for almost all genomes, with the notable exception of M. leprae, in which massive gene decay has been discovered, resulting in numerous long spacers containing pseudogenes (25). The fraction of non-coding DNA in the analyzed prokaryotic genomes varied from 5 to 50% (Table 1) however, for 90% of the genomes, the fraction of non-coding DNA was <18%, the major outliers being M. leprae and R. prowazekii, two genomes of bacterial parasites enriched in pseudogenes (25-27)." Genome size is 4215kb
Entered by Uri M
ID 105753