||Human Homo sapiens
||Mohr D, Frey S, Fischer T, Güttler T, Görlich D. Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO J. 2009 Sep 2 28(17):2541-53.PubMed ID19680228
||In this study researchers used a size series of 11 inert permeation probes with masses between 0.6 and 40 kDa to explore the permeability barrier of NPCs. The data obtained suggest a sieve-like barrier with a heterogeneous mesh size and a prevalent mesh radius of ˜2.6 nm. Researchers used permeabilized HeLa cells.
||This is far more narrow than the earlier assumed 4.5 nm (Paine et al, 1975 Keminer and Peters, 1999 BNID 104250).