Percent of embryos (cleavage stage, day 3) that are aneploid

Value 51.1 %
Organism Human Homo sapiens
Reference Fragouli E, Lenzi M, Ross R, Katz-Jaffe M, Schoolcraft WB, Wells D. Comprehensive molecular cytogenetic analysis of the human blastocyst stage. Hum Reprod. 2008 Nov23(11):2596-608PubMed ID18664475
Method comparative genomic hybridization (CGH)
Comments Previous CGH studies conducted at the cleavage stage (Day 3) revealed that 51% of embryos are aneuploid in all cells, 32% due to meiotic error, with a further 19% devoid of normal cells due to mitotic errors occurring after fertilization (Voullaire et al., 2000 PMID 10746563, Voullaire et al., 2007 PMID 17418829 Wells and Delhanty, 2000 PMID 11044470). See BNID 105361, 105366
Entered by Uri M
ID 105362