| Value |
13922
Unitless
|
| Organism |
Fruit fly Drosophila melanogaster |
| Reference |
Müller A, MacCallum RM, Sternberg MJ. Structural characterization of the human proteome. Genome Res. 2002 Nov 12 (11):1625-41. Table - link PubMed ID12421749
|
| Method |
A valuable tool in exploiting three-dimensional information
is the databases of protein structure in which domains
with similar three-dimensional architecture are grouped together.
Here, we use the structural classification of proteins
(SCOP)(Conte et al. 2000). In SCOP, protein domains of
known structure that are likely to be homologs are grouped by
an expert into a common superfamily based on their structural
similarity together with functional and evolutionary
considerations. SCOP is widely regarded as an accurate assess-ment of which domains are homologs. However, SCOP remains
subjective and one cannot exclude the possibility that
two domains placed within the same superfamily only share a
common fold as a result of convergent evolution and therefore
are not homologous. |
| Comments |
Key words give superfamilies of SCOP (Structural Classification of Proteins). There are 518 distinct superfamilies in Drosophila proteome. See Table for more details. FlyBase link gives 13831 protein coding genes, 18323 unique polypeptides and 21783 redundant protein coding transcripts (as of Oct 16 2009). See BNID 100200 and see value of 14,332 proteins in BNID 105464, Harrison et al 2003, table link - link |
| Entered by |
Uri M |
| ID |
104993 |