| Value |
40000
molecules/cell
|
| Organism |
Mouse Mus musculus |
| Reference |
Fujimoto J, Narayanan CS, Benjamin JE, Heinflink M, Gershengorn MC. Mechanism of regulation of thyrotropin-releasing hormone receptor messenger ribonucleic acid in stably transfected rat pituitary cells. Endocrinology. 1992 Apr130(4):1879-84PubMed ID1312428
|
| Method |
Researchers study the mechanism of regulation of TRH-R mRNA in a line of GH3 cells that are stably transfected with mouse pituitary TRH-R cDNA (GH-mTRHR-1 cells). |
| Comments |
Researchers developed a rat pituitary cell line, GH-mTRHR-1, that is stably transfected with a mouse pituitary TRH-R cDNA. GH-mTRHR-1 cells contain approximately 40,000 TRH-Rs/cell and respond to TRH with the expected generation of inositol lipid-derived second messengers. |
| Entered by |
Uri M |
| ID |
104207 |