Value |
7
sec^-1
|
Organism |
Bacteria Escherichia coli |
Reference |
Hani S. Zaher and Rachel Green, Fidelity at the Molecular Level: Lessons from Protein Synthesis. Cell Volume 136, Issue 4, 20 February 2009, Pages 746-762PubMed ID19239893
|
Primary Source |
Pape T, Wintermeyer W, Rodnina M. Induced fit in initial selection and proofreading of aminoacyl-tRNA on the ribosome. EMBO J. 1999 Jul 118(13):3800-7.PubMed ID10393195
|
Method |
pre-steady-state kinetic experiments. |
Comments |
Cognate=tRNA with correct codon. Near cognate=tRNA with single nucleotide mismatch in codon.Under conditions where GTPase activation (previous step in tRNA selection) does not limit accommodation |
Entered by |
Uri M |
ID |
103478 |