Level of accuracy of nucleotide incorporation in DNA replication

Range 1e-8-1e-10 mismatched/correct nucleotide
Organism Unspecified
Reference Hani S. Zaher and Rachel Green, Fidelity at the Molecular Level: Lessons from Protein Synthesis. Cell Volume 136, Issue 4, 20 February 2009, Pages 746-762PubMed ID19239893
Primary Source Kunkel and Bebenek, 2000 T.A. Kunkel and K. Bebenek, DNA replication fidelity, Annu. Rev. Biochem. 69 (2000), pp. 497–529.PubMed ID10966467
Comments This level of accuracy (1e-8-1e-10) is much higher than that of transcription and translation
Entered by Uri M
ID 103452