Number of histones in nucleosome core particle
| Value | 8 histones |
|---|---|
| Organism | Eukaryotes |
| Reference | Widom J. Structure, dynamics, and function of chromatin in vitro.Annu Rev Biophys Biomol Struct. 1998,27:285-327. p.287 4th paragraph & bottom paragraphPubMed ID9646870 |
| Method | X-ray crystallography |
| Comments | "The initial or lowest level of chromatin organization consists of the local wrapping of a short stretch of DNA, 147 bp in length, in ˜1.75 turns of a flat superhelix around an octameric histone protein core, which is composed of two molecules each of histones H2A, H2B, H3, and H4. This complex of the histone octamer and 147 bp of DNA is known as the nucleosome core particle." |
| Entered by | Uri M |
| ID | 102985 |