Size of the LacY transporter

Value ~ nanometer Range: 6 nm x 3 nm (on membrane surface) oval shaped nanometer
Organism Bacteria Escherichia coli
Reference Abramson J, Smirnova I, Kasho V, Verner G, Kaback HR, Iwata S. Structure and mechanism of the lactose permease of Escherichia coli. Science. 2003 Aug 1 301(5633):610-5. p.611 left column top paragraphPubMed ID12893935
Method crystal structure at 3.5 angstroms of the Escherichia coli lactose permease
Comments "Viewed parallel to the membrane, the monomer is heart-shaped with an internal cavity open on the cytoplasmic side and largest dimensions of 60 Å (along the membrane) by 60 Å (along the membrane normal). Normal to the membrane, the molecule is oval-shaped with dimensions of 30 Å by 60 Å. According to biochemical evidence (refs 10, 11), the membrane is estimated to be ~27 Å (fig.1A)"
Entered by Ron Milo - Admin
ID 102929