| Comments |
P.872 right column 4th paragraph: "Gene density is similar for chromosomes I and II, with one gene every 2,483 and 2,457 bp respectively, but is less dense for chromosome III, at one gene every 2,790 bp. This is not due to differences in the average length of the genes, which are similar (1,407–1,446 bp) for all three chromosomes (Table 1). Protein-coding genes are absent from the centromeres, although tRNA genes are found in these regions. Gene density is also lower at the telomeres. The gene density for the complete genome is one gene every 2,528 bp, compared with one gene every 2,088 bp for S. cerevisiae. The protein-coding sequence is predicted to occupy 60.2% (57% excluding introns) of the sequenced portion of the S. pombe genome, compared with 71% in S. cerevisiae (70.5% excluding introns). The overall guanine and cytosine (GC) content is 36.0%, compared with 38.3% in S. cerevisiae, and for the protein-coding portion is identical in the two yeasts at 39.6%." A better reference is needed. |