Value |
>=50
Fold
|
Organism |
Bacteria Escherichia coli |
Reference |
Oehler S, Eismann ER, Krämer H, Müller-Hill B,The three operators of the lac operon cooperate in repression,EMBO J. 1990 Apr9(4):973-9PubMed ID2182324
|
Method |
testing the effect of systematic destruction of all three lac operators of the chromosomal lac operon of Escherichia coli on repression by Lac repressor |
Comments |
With all three operators, O1,O2,O3 expression of beta-galactosidase is repressed 1300 Fold. destruction of 'pseudo operators' O2 and O3 results in 50 fold decrease in repression relative to 1300 |
Entered by |
Uri M |
ID |
102090 |