| Value |
90
%
|
| Organism |
Bacteria Escherichia coli |
| Reference |
X. Sunney Xie, Paul J. Choi, Gene-Wei Li, Nam Ki Lee, and Giuseppe Lia, 'Single-Molecule Approach to Molecular Biology in Living Bacterial Cells', Annu. Rev. Biophys. 2008. 37:p.427PubMed ID18573089
|
| Primary Source |
Elf J, Li G, Xie XS. 2007. Probing transcription factor dynamics at the single-molecule level in a living cell. Science 316:1191–94PubMed ID17525339
|
| Method |
from formula Deff = D3D(1 - F ) + FD1D/3,where F is above property and that the second term is negligible. Deff=0.4µm^2/sec, D3D=3µm^2/sec (Bions 102038,102039) |
| Comments |
This suggests that in searching for the operator, a lac repressor spends ~90% of its time nonspeci?cally bound to and diffusing along DNA |
| Entered by |
Uri M |
| ID |
102040 |