ATP requirement for growth on glucose and minimal media under aerobic conditions

Value 1.21e+10 ATP/cell
Organism Bacteria Escherichia coli
Reference Farmer, I.S. and Jones, C.W. The energetics of Escherichia coli during aerobic growth in continuous culture. (1976) Eur. J. Biochem. 67(1):115-22. abstact heading '3', p.119 right column 2nd paragraph & p.120 table 2 (value of 13.9 for YATP(max))PubMed ID786616
Method YATP(max) was determined by measuring the rate of oxygen consumption(QO2) and growth rate(D), and calculating the value of mol ATP formed per mol oxygen (N) and the energetic maintenance cost (M). The equation QO2 = D/YATP(max)×N + M/N was used.
Comments This number is calculated from the value for YATP(max) of 13.9 in the reference. YATP(max) is the number of grams of cells (dry weight) produced per mol of ATP corrected for cellular maintenance energy costs. 1/13.9 gives 0.0719 mol of ATP per gram of cells. One E.coli cell weighs 0.28pg (dry wt) BNID 103904, so there are 3.57 trillion cells/gram. 0.0719×6.02E23/(3.57E12 cells/g (dry wt)) gives 12.1 billion ATP/cell. See BNID 101983, 101982, 104847
Entered by Phil Mongiovi
ID 101981