RNA polymerase molecules per cell

Range 1500-11400 Table - link Unitless
Organism Bacteria Escherichia coli
Reference Bremer, H., Dennis, P. P. (1996) Modulation of chemical composition and other parameters of the cell by growth rate. Neidhardt, et al. eds. Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, 2nd ed. chapter 97, p.1559, Table 3 and note 'b' beneath table
Comments Note 'b' beneath table: "The number of core RNA polymerases per cell was calculated from ap [RNA polymerase protein/total protein] (this table) and values of Pc [protein per cell] (Table 2 link - link ), using aa/pol (Table 1 link - link ) and the relationship Np=Pc×αp/(aa/pol)." lower value is for slow division rate (100 minutes) and higher value is for fast division rate (24 minutes). Note-Jishage et al 1995 PMID 7592475 give value of 1,500-2,000 core enzyme RNAP/cell (citing Ishihama, A. 1991. Global control of gene expression in bacteria, p. 121–140. In A. Ishihama and H. Yoshikawa (ed.), Control of cell growth and division. Japan Scientific Society Press, Tokyo.)
Entered by Ron Milo - Admin
ID 101440