Mutation rate of HIV reverse transcriptase in cells
| Value | 3E-05 mutations per bp per cycle |
|---|---|
| Organism | HIV |
| Reference | Mansky LM, Temin HM. Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J Virol. 1995 Aug69(8):5087-94.PubMed ID7541846 |
| Method | Mutations in lacZ gene delivered by HIV shuttle vector |
| Comments | For value of 8.5×10^-5 mutations per bp per cycle see O'Neil et al., 2002 PMID 12151398 p.38059 table 1 |
| Entered by | Alex Sigal |
| ID | 100606 |