Range |
~2e+8 (prerRNA 39% pre-mRNA (hnRNA) 58% 4–5S RNA 3%) nts/min
|
Organism |
Mouse Mus musculus |
Reference |
Jackson DA, Pombo A, Iborra F. The balance sheet for transcription: an analysis of nuclear RNA metabolism in mammalian cells. FASEB J. 2000 Feb14(2):242-54. p.243 right column top paragraphPubMed ID10657981
|
Primary Source |
Brandhorst, B. P., and McConkey, E. H. (1974) Stability of nuclear RNA in mammalian cells. J. Mol. Biol. 85, 451–463PubMed ID22003578
|
Method |
"Kinetic analyses of the entry of [3H]adenosine into
ATP and RNA establish levels of RNA synthesis
within intact cells." |
Comments |
"Mouse L cells, which divide every 12–14 h, support a continuous synthetic rate of ~2×10^8 nucleotides/min with 39, 58, and 3% into prerRNA,
pre-mRNA (hnRNA), and 4–5S RNA, respectively
(primary source)." |
Entered by |
Uri M |
ID |
111160 |