| Range |
3 - 4 days
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 1992 Nov119(3):493-501. p.499 left columnPubMed ID1400587
|
| Primary Source |
Wright, N., and M. Alison. 1984. The Biology of Epithelial Cell Populations. Clarendon Press, Oxford. 537-891 and 981-1004. |
| Method |
pulse-chase experiments |
| Comments |
P.499 left column:"[Investigators'] prime objective in this work was to correlate the pattern of TUNEL [the method of TdT-mediated dUTP-biotin nick end labeling, see Method section in BNID 112334] staining in situ with data about systems in which PCD [programmed cell death] existence was already suspected through other means. The small intestine epithelium is typified by a high turnover rate (3-4 d for the replacement of the entire epithelium)
and well-defined architecture of repetitive proliferating units where the location of cells which are about to be disposed, is known through pulse-chase experiments (summarized
by primary source)." |
| Entered by |
Uri M |
| ID |
112335 |