Brain imaging: how stable are synaptic connections?

Curr Biol. 2003 Mar 4;13(5):R180-2. doi: 10.1016/s0960-9822(03)00118-0.

Abstract

Cortical circuits can undergo experience-dependent remodeling, while retaining the capacity for long-term information storage. The stability of individual synaptic connections is fundamental to both processes, but poorly understood; two studies using new in vivo imaging techniques have finally shed some light on this important issue.

MeSH terms

  • Animals
  • Brain / anatomy & histology*
  • Dendrites
  • Diagnostic Imaging*
  • Mice
  • Synapses*