Diffusion coefficients of lipids and GPI-linked proteins in cells

Range Table - link
Organism Various
Reference Saxton MJ, Jacobson K. Single-particle tracking: applications to membrane dynamics. Annu Rev Biophys Biomol Struct. 1997 26: 373-99. p.382 table 2PubMed ID9241424
Primary Source 22) Dai J, Sheetz MP. 1995. Axon membrane flows from the growth cone to the cell body. Cell 83: 693–701 (33) Edidin M, Kuo SC, Sheetz MP. Lateral movements of membrane glycoproteins restricted by dynamic cytoplasmic barriers. Science. 1991 Nov 29 254(5036):1379-82. (46) Hicks BW, Angelides KJ. Tracking movements of lipids and Thy1 molecules in the plasmalemma of living fibroblasts by fluorescence video microscopy with nanometer scale precision. J Membr Biol. 1995 Apr144(3):231-44. (50) Ishihara A, Hou Y, Jacobson K. The Thy-1 antigen exhibits rapid lateral diffusion in the plasma membrane of rodent lymphoid cells and fibroblasts. Proc Natl Acad Sci U S A. 1987 Mar84(5):1290-3. (60) Lee GM et al., Unconfined lateral diffusion and an estimate of pericellular matrix viscosity revealed by measuring the mobility of gold-tagged lipids.J Cell Biol. 1993 Jan120(1):25-35. (84) Sheets ED, Jacobson K. 1996. GPIanchored proteins and glycosphingolipids exhibit transient lateral confinement to small domains: a single particle tracking study. Biophys. J. 70: A335 (Abstr.)PubMed ID8521486, 1835798, 7658460, 2881297, 8416991
Method Results of SPT (single particle tracking) experiments, and the corresponding FRAP (fluorescence recovery after photobleaching) experiments when available, are summarized in the table.
Comments Primary sources numbered as in table. See footnotes of table 1 beneath table
Entered by Uri M
ID 106243