Amplitude of elementary Acetyl choline current pulse

Value 1E-11 Ampere
Organism Unspecified
Reference Katz B, Miledi R. The statistical nature of the acetycholine potential and its molecular components.J Physiol. 1972 Aug224(3):665-99.PubMed ID5071933
Method In vivo experiments were made on junctional regions of frog sartorius muscle fibres, by recording potential changes which resulted from application of acetylcholine or other depolarizing drugs.
Comments The elementary ACh current pulse (amplitude approximately 10^-11 A), arises from a conductance change of the order of 10^-10 Omega^-1 which lasts for approximately 1 ms (at 200 C), and produces a minute depolarization , of the order of 0.3 uV.
Entered by Uri M
ID 104138