RecA filament assembly and synapsis during replication and homologous recombination

Range Table - link
Organism Bacteria Escherichia coli
Reference Bell JC, Kowalczykowski SC. RecA: Regulation and Mechanism of a Molecular Search Engine. Trends Biochem Sci. 2016 Jun41(6):491-507. doi: 10.1016/j.tibs.2016.04.002 p.495 table 1PubMed ID27156117
Primary Source See refs beneath table
Comments P.494 top paragraph: "Owing to a rich history of elegant genetic and biochemical investigation of RecA, many of the biochemical and biophysical properties of RecA can be summarized in relation to the physiology of E. coli ( Table 1)." P.501 bottom paragraph: "The RecA–DNA complex is not a simple, compact entity, rather, it is a long partially flexible filament that has a persistence length (i.e., a measure of polymer stiffness) of ∼900 nm for the static ATPγS filament [primary source 44], which is approximately 20 times greater than dsDNA (45–50 nm primary source 80, ref 81) and several hundred times greater than ssDNA (0.6–3 nm primary sources 44, 82, ref 83) (Table 1)." See notes beneath table
Entered by Uri M
ID 114125