Difference between catalyzed and uncatalysed reaction in which OMP decarboxylase turns its substrate over

Value 20 order of magnitudes faster
Organism Budding yeast Saccharomyces cerevisiae
Reference Miller BG, Wolfenden R. Catalytic proficiency: the unusual case of OMP decarboxylase. Annu Rev Biochem. 2002 71: 847-85. DOI: 10.1146/annurev.biochem.71.110601.135446 abstractPubMed ID12045113
Comments Abstract: "5'-phosphate decarboxylase (ODCase) turns its substrate over with a half-time of 18 ms, in a reaction that proceeds in its absence with a half-time of 78 million years in neutral solution."
Entered by Uri M
ID 113581