Life span of autophagosomes

Value 32 min Range: Table - link min
Organism Mammalian tissue culture cell
Reference Fass E, Shvets E, Degani I, Hirschberg K, Elazar Z. Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes. J Biol Chem. 2006 Nov 24 281(47):36303-16. p.36312 table 1PubMed ID16963441
Method "To characterize the dynamics and intracellular route taken by autophagosomes in living cells, [researchers] established a CHO cell line that stably expresses GFP fused to the N terminus of LC3. The localization of GFP-LC3 in living cells was followed by confocal microscopy analysis."
Entered by Uri M
ID 110116