Concentration of highly expressed proteins

Range 1,000 to 3,000 Molecules/cell
Organism Bacteria Escherichia coli
Reference Roberts E, Magis A, Ortiz JO, Baumeister W, Luthey-Schulten Z. Noise contributions in an inducible genetic switch: a whole-cell simulation study. PLoS Comput Biol. 2011 Mar7(3):e1002010. doi: 10.1371/journal.pcbi.1002010. p.10 right column top paragraphPubMed ID21423716
Primary Source Taniguchi Y, Choi PJ, Li GW, Chen H, Babu M, Hearn J, Emili A, Xie XS. Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells. Science. 2010 Jul 30 329(5991):533-8.PubMed ID20671182
Comments "The value [2,500 molecules per cell for LacY mRNA] also falls within the range of 1000–3000 seen for other highly expressed proteins in E. coli [primary source]." See BNID 109052
Entered by Uri M
ID 109046