Distribution of signaling-related ATP usage among different cellular mechanisms when the mean firing rate of neurons is 4Hz
Range | Figure - link % |
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Organism | Eukaryotes |
Reference | Attwell D, Laughlin SB. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab. 2001 Oct21(10):1133-45. p.1140 figure 3PubMed ID11598490 |
Comments | "The percentages of the expenditure maintaining resting potentials, propagating action potentials through a neuron, and driving presynaptic Ca2+ entry, glutamate recycling, and postsynaptic ion fluxes, are shown (100% = 3.29×10^9 ATP/neuron/s)." For distribution [in rat neocortex] updated to account for mammalian action potentials using less energy than those in squid giant axon see Harris et al. 2012 p.764 figure 2A link |
Entered by | Uri M |
ID | 108673 |